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Cachexia in Cancer Patient

Updated: Jul 25, 2022

  • A syndrome that can be caused by multiple factors and is characterized by an ongoing loss of skeletal muscle mass (with or without a loss of fat mass) that cannot be reversed by conventional nutritional support and results in progressive functional impairment.

  • The pathophysiology of the condition is characterized by a negative balance of protein and energy, which is driven by a variable combination of decreased food intake and abnormal metabolism.

  • It has been suggested that the definition should be modified to include additional aspects, such as the level of C-reactive protein (CRP) and the loss of appetite.

  • Cachexia caused by cancer makes patients' quality of life worse and reduces their response to treatment, which in turn increases their risk of morbidity and mortality.

  • It is present in fifty percent of cancer patients and is responsible for twenty percent or more of cancer-related deaths.

what is cachexia
Cachexia in Cancer

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